Gil Grissom and Sara Sidle come to the aid of a former colleague who is implicated in tampering with evidence. Maxine and the rest of the CSI team work the murder of a couple slain on their wedding day, following the evidence to the salacious underbelly of the Las Vegas elite.

An abandoned horse covered in blood leads the CSI team to a halfway house for convicted murderers. Also, Grissom and Sara begin to circle their prime suspect in the David Hodges case.

The CSI team looks closely at the eccentric world of sideshows when a couple of performers are discovered burned in a pit. Also, Hodges mulls a plea deal as his criminal trial kicks off, while Max, Grissom and Sara search for evidence to exonerate him.

When David Hodges goes missing, the entire CSI team searches for any piece of evidence that can help locate him, clear his name and save the reputation of the entire crime lab.