Danny is unable to get custody of Evan. The gang try and save a baby elephant who has been abandoned. Danny finds himself pushed to the limit as a father and a vet.

Whilst they are on the run Danny and Evan come across a sick hippo. They put themselves on the line to try and help her. Rosie meets the new owner of Mara. Rosie put her own and the animal hospital's future at risk to help save a sick lioness.

Danny is called to help with a rabies outbreak. Danny finds it hard working with a vet called Alice who has been sent to help him.

Max and Rosie are finally married but their future happiness is in jeopardy. Du Plessis is upset when he finds out that Caroline has decided not to return to Africa.

Danny and Alice rescue an endangered wild dog and are shocked by the arrival of Alice's ex boyfriend who shows up to take a look at the animal. When Terry manages to persuade Alice to give them another go, Danny realises he has to be honest about how he feels about her.

Du Pleiss shocks everyone when he says he is returning to the United Kingdom to live with Caroline and that he wont be coming back. Rosie is determined to stop some animals from being treated badly.

Georgina thinks that Du Plessis is South Africa's version of Crocodile Dundee. An animal's welfare is in jeopardy when he lets fame go to his head. A man shows up claiming that a lioness belongs to him and he is determined to get the animal back.

Danny and Alice fall out at an animal auction. Alice becomes upset when she thinks she has paushed Danny towards Vanessa. A storm hits the area and Alice is concerned that she might not get the chance to be honest with Danny about how she really feels.

Alice is forced to leave Danny and try and get help following the storm. After Alice makes it back to Mara a search party heads out to find him. Danny leaves the car when he needs water and finds himself in real danger.

Danny has to fix the reserve's boundaries after some of the animals are discovered roaming around in the town following the storm. Vanessa fires Fatani after he steals some medicine to help a sick elephant calve. Du Plessis is surprised by Caroline's arrival at the Family Day Festival organised by Georgina.

Back among the lions, giraffes and elephants, love is continuing to blossom for Danny Trevanion and fellow vet Alice Collins but will Danny have the courage to commit to her? Throughout the series the pair will face many challenges, not least the pressure of working together, and Alice must make some difficult decisions about her future at Leopard’s Den.

Danny starts to feel his age after hurting his back whilst building a new local school. When a new young vet arrives called Lewis he feels even older. After Caroline requests that Du Plessis organises their honeymoon, she ends up with much more than she bargained for.

Alice becomes increasingly torn between helping Rowan to rehabilitate a tiger at Mara and her own responsibilities at Leopard's Den. Danny's project to help township animals takes a disastrous turn when a pregnant cow develops complications. Du Plessis and Fatani agree to help with Rowan's beauty pageant

Danny confides in Du Plessis about his intention to ask for Alice's hand in marriage, but the arrival of his step-daughter Olivia threatens to derail his plans. Meanwhile, Jana the cheetah falls sick, and Danny realises that he must save the animal if he is to salvage his relationship with Olivia.

Danny and Alice's plans for a romantic trip away are ruined when they come across a crash out in the bush. With an injured tourist on their hands and a lion on the loose, they are faced with a long, dark night ahead. Meanwhile, Du Plessis decides that it is time that Olivia learned some manners, but will his short, sharp technique do the job?

Danny's attempts to help Alice settle into her new job at Mara backfire when a hyena goes on the rampage. With the life of an animal in the balance, Danny realises he must pull out all the stops if he is to salvage his relationship with Alice. Meanwhile, Alice discovers that Rowan and Vanessa have been seeing each other in secret. And a honeymooning couple face a charging wildebeest.

With matters between him and Alice still tense, a distracted Danny makes a fatal mistake while treating a rare black leopard. When the big cat dies, its owner insists that Danny is investigated for malpractice. Hearing the bad news, Du Plessis decides to look into the matter in order to exonerate his friend. But things look bleak when Danny goes against his suspension to treat Jana and an official catches him out.

Leopard’s Den’s residents go to an auction to purchase a giraffe after lions kill their own. However when Danny and Alice argue over a suitable replacement Danny falls into the arms of Vanessa. Meanwhile, a storm is approaching Leopard’s Den, so for safety reasons the family have to release some of the animals. When the storm hits, Charlotte and Danny come off the worst.

There are dangerous consequences when Du Plessis ignores his heart condition and collapses while alone in the bush. Danny gets more than he bargained for when he has to deal with two rogue lions that are attacking the local cattle. Olivia and Caroline are finding it particularly hard as the anniversary of Sarah's death draws nearer.

When Du Plessis hears about Caroline's intention of buying them a retirement home he confesses to Olivia that he has given away all of their savings to his son. Will they be able to resolve the situation before the family find out? Danny and Alice's plan to give a home to a rare aardwolf backfires when they meet Vanessa's father - who refuses to take in charity cases. He goes on to make himself even more unpopular by buying Ekotto's land with the intention of turning it into a golf course.