In the Season 13 premiere, Nichole, 25, has constant tremors due to a severe alcohol addiction as she struggles to overcome the pain of her sister s betrayal.

Elena, 63, has no intentions of stopping her daily meth addiction, even though her children and grandchildren desperately want their adoring grandmother to get well.

Twenty-five year-old Katie uses her eating disorder and binge drinking to cope with her mother's secret alcoholism and parents war with each other while her worried siblings pray someone can step in and save them all.

Once a big-hearted Christian family man, Dennis uses his meth and alcohol addiction to run from the past that haunts him, while his family falls apart.

Former "Super Mom" to her three children, Diana has exchanged her apron for an alcohol and meth addiction and is unraveling her marriage, family and sense of self-respect.

A family begging her to get help and two overdoses in the last two weeks don t phase 21-year-old Britney as she fearlessly shoots up suboxone and bath salts up to 30 times a day. Terry, 32, is a chef who dreamed of opening and managing his own restaurant, but his career, marriage and parental rights to his nine-year-old daughter have hit a dead end as a result of his $500 a day cocaine and fentanyl addiction.

Thirty-one year-old Amanda has exchanged her dreams of teaching for an alcohol and crack addiction, while her family erupts in anger over her dad's chronic enabling.

Attractive, charismatic 41year-old twins, Susie and Miriam, battle crack and alcohol addictions and each other as their career success and families slowly slip away.

Ryan, 25, is a sweet, sensitive man whose alcohol addiction is spiraling out of control as he and his fiance are expecting their first child in a matter of months.

Loud and spunky 50 year-old Cher's alcohol addiction has led to liver damage and is driving a wedge between herself and her family.

Al, a big guy with a big personality, is sacrificing his relationships with his wife and children to chase his out-of-control meth and painkiller addiction.

Kelly, a 27-year-old mother of three, mixes pills and meth to forget the man who destroyed her childhood.

Sandi, 64, is a vivacious, spunky and fun grandmother who loves gardening. But as her drinking escalates throughout the day, Sandi turns her gin-fueled anger on her 88-year-old mother and her 45-year-old daughter, alienating everyone in her wake. Can Sandi make peace with her estranged family and get the help she needs before it's too late?

Charismatic businessman, spiritual leader and father, 56-year-old Terry is destroying his legacy with his crack addiction and taking his adoring son down with him. Alissa, 19 is a smart and fearless teenager who uses bath salts to mask her inner pain. Alissa must make peace with her estranged father in order to break free from her dangerous lifestyle and her self-destructive cycle.

When her rock and best friend, her grandmother Elena, went away to treatment, Sarah, 21, spiraled out of control. Today, in denial of her own addiction, Sarah is on the same path of addiction her grandmother was on just six months ago. This cycle of addiction must stop in this family now, or unfortunately, Elena will pass on a legacy of addiction instead of recovery.

Tiffany is a 19-year-old, doe-eyed, innocent looking young woman who treks to the seediest parts of Baltimore to score heroin while her family tries to pray the "devil" out of her.

After losing her children, 32 year-old Dana spirals into a severe drug addiction to numb her pain while her desperate, grieving family pleads with her to stop.

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In an Intervention first that reveals a surprising outcome, we reach out to 18-year-old Andrew who once dreamed of a military career, but now binges and purges up to 12 times a day.