On a mission for President Grant, agent West travels to Fort Savage to meet with a Major Jason and help prevent a revoloution in Canada that outlaw Shawn O'Riley has plans to incite. At the fort, West reads a description of O'Riley and realizes too late his striking resemblance to Major Jason. O'Riley announces that he now controls the fort and is holding the real major and his men captive. Meanwhile, Gordon has gone under cover to learn the details of the revolution. He arrives at West's side just as his partner is trapped on wrong side of O'Riley's gun.

Something is happening in the small town of New Athens. residents are leaving in droves,scared off by a band of seedy cut-throats gathering just outside the town limits. And then there's Michael Trayne,back in town after three years in jail. Can Jim and Arte figure out what's happening and save the town before everyone leaves permanently?

Agent James West attempts to rescue a man called Mr.Markham from a masked assailant who flees the scene of the crime. As Markham lays dying,he utters two words-""enzo"" and ""silver"". Meanwhile,Agent Artemus Gordon has joined a troupe of entertainers traveling to Denver under the leadership of casino operator Kohner. Gordon,who is posing as a Shakespearean actor,learns that a man called Enzo has a girl friend,Topaze. She is a dancer with the troupe,probably working under an assumed name,and is on her way to meet Enzo in Denver. Dierdre,a dancer,attempts to pass some information to West but a jealous Kohner interrupts them and engages the agent in a fight with him and El Bardhoom,a huge weight lifter. Later,Artemus hears a strange voice of Markham's masked Killer. When West goes to meet Dierdre at midnight,he discovers that she too been slain by unseen assailant.

On a dusty Californian trail,Jim and Artemus intercept a stagecoach whose driver has been hired to smuggle boll weevils. Quickly theorizing that someone is trying to destroy the country's cotton crop,they set out to find the mastermind of the operation and destroy his distribution system before his plan succeeds.