The town takes in a group of 'working girls' escaping from their vengeful master.

The Seven go their separate ways when a Federal Marshal takes control of the town. The cattle barons band together to take the now unprotected town. The Seven are forced to reunite to save the townsfolk.

The Seven protect a wagon train when the settlers are threatened by a demanding gold-hunter who claims he owns the land. Vin falls in love with Charlotte, wife to the abusive wagon master. Chris, Vin, Buck, and Ezra ride to rescue Charlotte after she's kidnapped and held ransom. Buck and Ezra try to win a widow's hand by charming her pudgy young son.

The boys continue to protest the wagon train from Dicky O'Shea and his dynamite expert. Vin and Charlotte return to the group and face the wrath of her husband, to warn of an impending attack. Mary decides to marry Gerard, reasoning that Billy needs a father.

The Seven investigate possible abuse of Chinese laborers by railroad foremen. Ezra buys a Chinese girl to stop her from being abused. Buck purchases a love potion to win Inez's heart.