The McCoys move from Smokey Corners, West Virginia., to a ranch in Fernando Valley, Calif., which Grampa McCoy has inherited from his brother Ben. They have also inherited Pepino, a ranch hand, and they meet their neighbors, Flora and George MacMichael. But Grampa finds himself homesick for ""West Virginny.""

The McCoys start a roadside eggstand and, inadvertently, an egg war with neighbor Harry Poulson.

The male McCoys try to outwit the female members by using money in the cookie jar to buy a shotgun rather than a dress for Kate to attend the PTA meeting. When the men concede defeat and they buy Kate a dress, things get even worse. Fortunately, the PTA president is able to correct their choice of dress.

Grampa thinks he's made a sharp business deal when he sells some useless farm land, until he finds out the freeway is going through that part of their land. Luke and Kate feel Grampa has been swindled -- but Grampa's native honesty saves the day for the McCoys.

When Grampa thinks Luke is being henpecked by Kate, Luke decides to prove him wrong—and ends up sleeping on the couch in the living room.

Luke and Kate urge Grampa to invite Flora MacMichael as his date to attend the Valley Ranchers annual fall dance and box supper. Grampa will have none of it until he hears that Flora is the best cook in the county.