Mike Jr. is upset when he sees a copy of his parents' divorce decree and gets into the sacramental wine at St. Vincent's, leading Mike to realize the importance of spending more time with his son; Grizz's high school sweetheart comes back into his life when she divorces her husband and comes to work at the parish; the cop who arrested Mike is mounting a case against Marcellus and asks Mike to flip on his former partner; when the cop's son is murdered during a robbery, Marcellus is assigned the case, which goes cold when the only witness is murdered; Mike and Marcellus join forces to find the cop before he administers some street justice to his son's killer; Marcellus offers to help his nemesis cover up his execution of the killer, but the cop declines and turns himself in, giving Marcellus a chance to get out from under his corrupt behavior.

Romantic feelings resurface between Olshansky and his high school girlfriend as he reconnects with her while trying to help her schizophrenic sister.

An exhausted E.R. doctor's error results in a man's death, and an upset Heather seeks Mike's help when the hospital administration refuses to take action after she reveals that the doctor falsified the man's chart to cover up his mistake; Mike convinces a reluctant Heather to give the story to reporter Emily Carson, whose investigation results in Heather's being fired and blacklisted on a trumped-up charge; Mike's concern that Heather may have to move far from Philadelphia with Mikey to find work puts a strain on his budding relationship with Faith, who begins to doubt that Mike is over Heather; Mike enlists the help of Ryan Ambrose, a psychiatrist at the hospital who supports Heather, in obtaining information that convinces the E.R. doctor to back up Heather's account of the patient's death and to admit his mistakes to Emily; Heather is reinstated, and she and Mike realize that it's over after spending the night together, leaving Mike free to commit himself to a relationship with Fait

After Bill Olshansky has heart attack which creates irreversible and uncurable heart damage, Mike's decision to take care of his father leads them over rough territory as they hash out old grievances and can't seem to connect; in an attempt to get them to reconcile, Faith provides some words of wisdom for both father and son which finally enables them to bridge the gulf that separates them before Bill dies; picking up on Mike's feelings about Ryan, Mikey begins acting out towards the new man in his mother's life; Grizz is suspended by the bishop after $2,000 is missing from the collection money; Mike enlists the help of Aldo and the altar boys in exposing the real thief; Grizz contemplates leaving the priesthood in the face of his growing attraction to Beth, coupled with the bishop's lack of confidence and support.