When the coronavirus pandemic hits Holby ED, Connie struggles to protect her team, Will becomes disillusioned with his work and Fenisha rushes to keep her baby safe.
Jacob wants more from Connie, but will she be able to make the time for their relationship with mounting pressures on the ED and an increasingly disillusioned Will.
An exhausted Will tries to make peace with the ED on his last day, Robyn does everything she can to help a conflicted patient, and Rash plucks up the courage to get himself a date.
Jacob’s life is thrown into peril when a suspected bomber enters the emergency department, and an exhausted Marty struggles to accept his father’s attempts at reconciliation.
In her moment of crisis, can Fenisha let Ethan in? Grace turns out not to be the little girl Connie expected, and Rosa encourages Ollie to try his luck.
Can Jan make the ultimate sacrifice to save her son? Faith and Lev do everything they can to keep their marriage together, and Connie interferes in Grace’s love life.
Jan’s fear is tearing her apart as she desperately tries to keep her son safe. Connie takes out her frustrations on Jacob’s new relationship, and a bit of fun accidentally leads Charlie to create a betting ring.
Jade’s confidence is crushed when a night out turns to disaster, Fenisha discovers the painful truth about Ethan’s diagnosis, and Tina pushes her luck with Jacob.
Rash’s past is revealed when an old friend arrives in the ED. Iain and Faith bond as they treat a dementia patient and her adoring husband. And Tina reminisces about her grief for Nat.
Fenisha’s life is thrown into disarray when a familiar face from her past appears. Rash fights to prove his competence, and Marty goes the extra mile to support women’s issues.
Lev finally admits the truth about his sexuality, Rash glimpses Tina’s manipulative side, and Charlie is left reeling when he’s accused of breaking up a marriage.
As Fenisha and Ethan prepare for their big day, Matthew battles his emotions, Lev faces up to his sexuality once and for all, and Ollie’s mystery illness is finally diagnosed.