In the year 2024, the ozone layer is believed to have been destroyed, and it's up to MacLeod and Ramirez to set things right. Opposition comes from both the planet Ziest (MacLeod and Ramirez's homeworld) and a corporation profiting from the supposed lack of ozone. Also, flashbacks show the story behind MacLeod and Ramirez's exile from Ziest.

All around the planet hundreds of millions of people are waiting for events to unfold in the year 2012, that they… believe will bring either the birth of a harmonious new reality… or ‘the end of the world. But what if those events were actually to take place THIS YEAR, in 2011? In “Awakening As One’s” new film “The Quickening” we will explain why so many people have been experiencing the sensation that “Time is Speeding Up”; particularly since the Earthquake in Japan. And we will also show how research indicates that this accelerated experience of reality could peak sometime around October 28th, 2011; culminating in a global experience of Unity Consciousness, which would then lead to the experience of a harmonious new way of being. “The Quickening” will also take a look at the unfolding of current events and how they directly relate to Hopi and Mayan Prophecies, indicating that we are on the Cusp of Great Changes, which signify the shifting of the Age… and the Birth of a New World.

Fourteen years after Third Impact, Shinji Ikari awakens to a world he does not remember. He hasn't aged. Much of Earth is laid in ruins, NERV has been dismantled, and people who he once protected have turned against him. Befriending the enigmatic Kaworu Nagisa, Shinji continues the fight against the angels and realizes the fighting is far from over, even when it could be against his former allies. The characters' struggles continue amidst the battles against the angels and each other, spiraling down to what could inevitably be the end of the world.