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Boxer "Irish" Micky Ward's unlikely road to the world light welterweight title. His Rocky-like rise was shepherded by half-brother Dicky, a boxer-turned-trainer who rebounded in life after nearly being KO'd by drugs and crime.
When terrorist action releases a secret government virus in the Houston Federal building, the employees become aggressive and homicidal. Federal officials quarantine the building to wipe out the infected and control the story, but a small group of uninfected are fighting to get out.