A beautiful temptress re-kindles an old romance while trying to escape her past during a tension-packed train journey.

Glendon Wasey is a fortune hunter looking for a fast track out of China. Gloria Tatlock is a missionary nurse seeking the curing powers of opium for her patients. Fate sets them on a hectic, exotic, and even romantic quest for stolen drugs. But they are up against every thug and smuggler in Shangai.

What happens when a glamorous express, with high government officials, wealthy merchants, concubines and a gang of brigands on board, speeds towards the small town of Hanshui, where escaping bank robbers, corrupt officials, and gamblers await? Well, let's just say the Titanic had a smoother maiden voyage.

Mysterious and unearthly deaths start to occur while Professor Saxton is transporting the frozen remains of a primitive humanoid creature he found in Manchuria back to Europe.