A teacher from New York moves to a small town in Texas, gets fired for being gay, and returns disguised in drag to get revenge on the people who were nasty to him.

After winning over the staff and students of Milford High School, chemistry teacher Richard Martinez aka Bianca Del Rio sent her nemesis Vice Principal Deborah “Debbie” Ward to jail in a flawlessly executed plan. When Debbie is released from jail, she conjures up a scheme to do away with Bianca Del Rio once and for all, by luring her on a dangerous journey to Russia to accept a teaching award and cash prize.

Richard Martinez is lured back into a decades-old feud with his mother, who owns a homophobic fast-food chain restaurant, and he decides to go under-cover as Bianca Del Rio to put her out of business.