It's 2 A.M. in St. Louis when a routine scientific experiment goes terribly wrong and an explosion shakes the city. A scientific team investigates, clashing with an intergalactic, voltage-devouring creature that vaporizes them.

The explorer craft USS Palomino is returning to Earth after a fruitless 18-month search for extra-terrestrial life when the crew comes upon a supposedly lost ship, the USS Cygnus, hovering near a black hole. The ship is controlled by Dr. Hans Reinhardt and his monstrous robot companion, but the initial wonderment and awe the Palomino crew feel for the ship and its resistance to the power of the black hole turn to horror as they uncover Reinhardt's plans.

Scientists try to simulate the Big Bang and the experiment gets out of control. While satellites come down and chaos arises, the stories of several people trying to survive is told.