After managing to survive attacks by Zeon's Char Aznable and Garma Zabi, the crew of Federation warship White Base and its mobile suits must battle Zeon forces through Asia, Europe, and the Atlantic Ocean if they are to reach Earth Federation's headquarters alive. During that process many of its crewmembers must overcome their fears, losses, immaturities, and insecurities in order to survive.

In the year UC 0071, three years after escaping the Zabi faction on an Ocean Cargo ship, Artesia and Casval are living happily in Andalusia, Spain, Earth under the identities of Sayla Mass and Éduoard Mass, respectively; masquerading as the children of Don Teabolo Mass, a long time friend of their father Zeon Zum Deikun.