On their way to Spring Break, college kids take a detour through an old Southern town. The people of Pleasant Valley insist the kids stay for their annual barbecue celebration... but instead of getting a taste of the old South, the old South gets a taste of them!

When this year's round of unsuspecting Northerners fail to show up for their annual Guts N' Glory Jamboree, the residents of Pleasant Valley take their cannibalistic carnival on the road and head to Iowa where they encounter spoiled heiresses Rome & Tina Sheraton and the cast and crew of their "Road Rascals" reality show. Performing "The Bloodiest Show on Earth", our Southern Maniacs prove more than ratings killers in what John Landis has called "one of the rare sequels that surpasses the original".

Six people are lured into a small Deep South town for a Centennial celebration where the residents proceed to kill them one by one as revenge for the town's destruction during the Civil War.