Æon Flux is set in a bizarre, dystopian future world. The title character is a tall, leather-clad secret agent from the nation of Monica, skilled in assassination and acrobatics. Her mission is to infiltrate the strongholds of the neighboring country of Bregna, which is led by her sometimes-nemesis and sometimes-lover Trevor Goodchild. Monica represents a dynamic anarchist society, while Bregna embodies a police state.

Set in a post-apocalyptic near future where countries no longer exist, reduced to Spartan like city-states locked in perpetual war, where children are turned into lethal soldiers and every citizen carries a gun, one young woman rises up to rebel against her Orwellian government as she becomes the hero known as Æon Flux. A live-action TV adaptation of the animated series.