Oscar De La Hoya vs. Floyd Mayweather Jr., billed as The World Awaits, was a light middleweight superfight that took place on May 5, 2007, at the MGM Grand Arena in Las Vegas, Nevada between six-division world champion Oscar De La Hoya (38–4, 30 KO) and undefeated four-division champion Floyd Mayweather Jr. (37–0, 24 KO). At the time, the bout was the most lucrative boxing match ever, with over $130 million in generated revenue.

Félix Trinidad vs. Oscar De La Hoya, billed as The Fight of the Millennium, was a boxing match held at the Mandalay Bay Events Center on the Las Vegas Strip on September 18, 1999, to unify the WBC and IBF's world Welterweight championships.

Bernard Hopkins vs. Oscar De La Hoya, billed as "History", was a professional boxing match contested on September 18, 2004 for Hopkins' WBA, WBC, IBF, The Ring and lineal middleweight championships, and De La Hoya's WBO middleweight championship.

A boxing fight.

Billed as "Ultimate Revenge", on September 18, 1998 for the WBC and lineal welterweight championships.

On June 7, 1996, Oscar De La Hoya fought Mexican legend Julio César Chávez (96–1–1) for the Lineal & WBC Light-welterweight championship. De la Hoya, with a record of 21–0 with 19 K.Os, defeated Chavez by a fourth round TKO. The fight was stopped due to a bad cut suffered by Chavez. Until their rematch in 1998, Chávez stated that De La Hoya did not defeat him since the fight was stopped. De La Hoya successfully defended his titles with a twelve round unanimous decision against undefeated former WBC Lightweight Champion and number one light welterweight contender Miguel Ángel González (41–0–0).

Oscar De La Hoya vs. Julio César Chávez II, billed as "Ultimate Revenge", was a professional boxing match contested on September 18, 1998 for the WBC and lineal welterweight championships.