A short Arizona motorcycle cop gets his wish and is promoted to Homicide following the mysterious murder of a hermit. He is forced to confront his illusions about himself and those around him in order to solve the case, eventually returning to solitude in the desert.

While working in a greenhouse, a man receives an insect bite after touching an exotic plant. Immediately, he falls ill and is taken to an emergency room where the doctors diagnose him as suffering from an unknown bacteria, and a strange parasite which emerges from his mouth as a large slimy wormlike creature. Soon, there are more cases of bacterial infection, but the more immediate problem for the hospital is the wormlike creature which after accidental exposure to a genetic growth stimulant grows to monstrous proportions and starts a reign of terror and bloodshed in the hospitals abandoned wing.

Researchers on the undersea lab Aquatica have genetically altered the brains of captive sharks to develop a cure for Alzheimer's disease. But there's an unexpected side effect: the sharks got smarter, faster, and more dangerous. After a big storm damages their remote research facility, they must fight for their lives.

The mafia's Paul Vitti is back in prison and will need some serious counseling when he gets out. Naturally, he returns to his analyst Dr. Ben Sobel for help and finds that Sobel needs some serious help himself as he has inherited the family practice, as well as an excess stock of stress.

Dr. Emma Collins and her team are spending their third summer on the island of Little Happy studying the effect of climate change on the great white sharks who come to the nearby nursery every year to give birth. Along with the last two inhabitants of this former fishing village, their peaceful life is disrupted when a "scientific" team led by her ex-boyfriend and marine biologist Richard show up looking for three bull sharks who we soon learn aren't just any bull sharks.

When shark conservationist Dr. Misty Calhoun is invited to consult on a top-secret project run by pharmaceutical billionaire Carl Durant, she is shocked to learn that the company is using unpredictable and highly aggressive bull sharks as its test subjects, which soon break loose and cause havoc.