Every evening, Eugène Fortin becomes Madame Simone, to the delight of club-goers around town. His flamboyant costumes, a pastiche of many styles, give him the look of a clown from the end of the last century. One day, Madame Simone hears a voice urging him to go to the Wigstock festival in New York: a gathering dear to both transvestites and wig fans.

Simon, a deeply religious man living in the 4th century, wants to be nearer to God so he climbs a column. The Devil wants him come down to Earth and is trying to seduce him.