Acting

—		American Dream: The 21 Savage Story
—		Klara and the Sun

2025

as (voice)

2023

as Rachel

2022		Glass Onion: A Knives Out Mystery as Natasha Lyonne
2022		DC League of Super-Pets as Merton (voice)
2022		House Comes with a Bird as Penn

2021

as Tallulah Bankhead

2020		Lip Service as Risa The VO Agent
2020		Irresistible as Tina
2020		Mae West: Dirty Blonde as Self
2020		Have a Good Trip: Adventures in Psychedelics as Self
2020		Love, Loss, and What I Wore

2019		John Mulaney & The Sack Lunch Bunch as Natasha Lyonne
2019		Honey Boy as Mom
2019		Ad Astra as Tanya Pincus
2019		Uncut Gems as Boston Player Personnel (voice)
2019		Long Gone as Carla Meola

2018		Family as Juggalette (uncredited)
2018		Doulo as Rena
2018		Show Dogs as Mattie
2018		A Futile and Stupid Gesture as Anne Beatts

2017		Night of Too Many Stars: America Unites for Autism Programs as Self
2017		Cabiria, Charity, Chastity as Jules
2017		Handsome: A Netflix Mystery Movie as Detective Fleur Scozzari
2017		Girlfriend's Day as Mrs. Taft

2016		The Realest Real as Herself
2016		Antibirth as Lou
2016		The Intervention as Sarah
2016		Yoga Hosers as Tabitha
2016		Adam Green's Aladdin as Mom
2016		Jack Goes Home as Nancy
2016		Darby Forever

2015		Hello, My Name Is Doris as Sally
2015		#Horror as Emma
2015		Addicted to Fresno as Martha
2015		Sleeping with Other People as Kara
2015		Bloomin Mud Shuffle as Jock

2014		The Quitter as Gloria
2014		Loitering with Intent as Kaplan
2014		G.B.F. as Ms. Hoegel

2013		7E as Yael
2013		Clutter as Lisa Bradford
2013		He's Way More Famous Than You as Natasha Lyonne
2013		The Rambler as Cheryl

2012		Girl Most Likely as Allyson
2012		American Reunion as Jessica
2012		4:44 Last Day on Earth as Tina

2011

as Mrs. Keaton

2010		The Immaculate Conception of Little Dizzle as Tracy
2010		All About Evil as Deborah Tennis
2010		Heterosexuals as Ellia
2010		Jelly as Mona Hammel
2010		Gavin McInnes is a Fucking Asshole as Self (archive footage)

2009		Goyband as Fani
2009		Running Away with Blackie as Motel Clerk
2009		Loving Leah as Esther
2009		Outrage: Born in Terror as Molly

2008

as Sally

2005		America Brown as Vera
2005		Nightstalkers, Daywalkers, and Familiars: Inside the World of 'Blade Trinity' as Self
2005		Robots as Loretta Geargrinder (voice)
2005		My Suicidal Sweetheart as Grace

2004		Blade: Trinity as Sommerfield
2004		Madhouse as Alice
2004		American Pie: Revealed as Self

2003		Die, Mommie, Die! as Edith Sussman
2003		Party Monster as Brooke

2002		Comic Book Villains as Judy
2002		Zig Zag as Jenna the Working Girl
2002		Night at the Golden Eagle as Amber

2001		Kate & Leopold as Darci
2001		The Grey Zone as Rosa
2001		American Pie 2 as Jessica
2001		Scary Movie 2 as Megan
2001		Fast Sofa as Tamara Jenson
2001		Plan B as Kaye

2000		But I'm a Cheerleader as Megan
2000		Freeway II: Confessions of a Trickbaby as Crystal ‘White Girl’ Van Meuther
2000		If These Walls Could Talk 2 as Jeanne

1999		The Auteur Theory as Rosemary Olsen - Finalist
1999		Detroit Rock City as Christine
1999		American Pie as Jessica

1998		Modern Vampires as Rachel
1998		Slums of Beverly Hills as Vivian Abromowitz
1998		Krippendorf's Tribe as Shelly

1996

as Djuna 'D.J.' Berlin

1993

as Polly

1990

as Arab Girl

1986

as Rachel's Niece (uncredited)

Production

2024

… Executive Producer

2023

… Executive Producer

2022		Crush … Producer
2022		Sirens … Executive Producer

2020

… Executive Producer

2016

… Producer

2000

… Associate Producer

Directing

2024

… Director

2020

… Director

2017

… Director

Writing

2020

… Writer

2017

… Writer