Dette er historien om Butch Cassidys skæbne efter han og The Sundance Kid stødte ind i den bolivianske hær i 1908, i slutningen af Butch Cassidy and the Sundance Kid. Nu går han under navnet James Blackthorn. Han er blevet gammel og drømmer bare om at se sit hjem en sidste gang. Derfor bevæger han sig ud på en lang rejse, og undervejs møder han en ung bankrøver, der får trukket ham med på et sidste eventyr.

The girlfriend of the Sundance Kid is on the run, with a price on her head, when she hears rumors that Sundance may still be alive.

Ready to quit their life of crime, the three "most-wanted" outlaws in the West---Butch Cassidy, Sundance Kid and Bill Carver ---perform their final job by robbing and stealing a train and fleeing across the border. In a South American town they begin their life of respectability by purchasing a ranch and depositing their stolen fortune in the local bank, and throwing a big fiesta to entertain the locals, including Colonel Aguilar and his beautiful daughter Rita.

The historical account of outlaws Butch Cassidy and the Sundance Kid, whose turn of the last century exploits made headlines, led them to be pursued by Pinkerton detectives hired by the railroads, and inspired a hit 1969 film.