Stef Foster, a dedicated police officer, and her partner Lena Adams, a school vice principal, have built a close-knit, loving family with Stef's biological son from a previous marriage, Brandon, and their adopted twins, Mariana and Jesus. Their lives are disrupted in unexpected ways when Lena meets Callie, a hardened teen with an abusive past who has spent her life in and out of foster homes. Lena and Stef welcome Callie and her brother, Jude, into their home thinking it's just for a few weeks, until a more permanent placement can be found. But life has something else in store for the Fosters.

Los Angeles couple Bryan and David have successful careers and a loving relationship and are ready for a baby. Just as they start to worry that they will never be blessed with parenthood, they meet Goldie, a waitress who has just moved to California with her precocious eight-year-old daughter to escape from her closed-minded grandmother and a life without a future. The guys quickly work out a deal with Goldie to become their surrogate, and in the process, the little group forms a unique family unit of its own.

Best friends Lizzy (gay and a bit type-A) and Luke (straight and more laid back) are like family. When they were kids and both of their parents were getting divorces, they stuck together, and they've been there for each other ever since. Now, all grown up and still single, they've decided to start a family of their own. No, not like that (there are some lines even they won't cross) - we're talking the non-romantic, go-to-the-doctor's-office type of baby-making.

Sean Saves the World is an upcoming American television series starring Sean Hayes. The multi-camera comedy is expected to air on NBC as part of the 2013–14 American television season. The series is set to premiere on October 3, 2013, and will air in the Thursday 9 pm time slot.