ნიუ იორკი, 1933 წელი. ამბიციური კინო პროდიუსერი მის გუნდსა და დაქირავებული გემის ეკიპაჟს თავის ქალის საიდუმლო კუნძულზე გამგზავრებას აიძულებს, სადაც ისინი შეხვებიან კონგს, უზარმაზარ მაიმუნს, რომელსაც მთავარი როლის შემსრულებელი ქალბატონი ანა დაროუ იმწამსვე გონს დააკარგვინებს.

Primatologist Davis Okoye shares an unshakable bond with George, the extraordinarily intelligent, silverback gorilla who has been in his care since birth. But a rogue genetic experiment gone awry mutates this gentle ape into a raging creature of enormous size. To make matters worse, it’s soon discovered there are other similarly altered animals. As these newly created alpha predators tear across North America, destroying everything in their path, Okoye teams with a discredited genetic engineer to secure an antidote, fighting his way through an ever-changing battlefield, not only to halt a global catastrophe but to save the fearsome creature that was once his friend.

After becoming injected with a formula derived from an alien ship, a lab gorilla escapes from his containment and befriends two young boys. The alien formula causes the gorilla to grow to gargantuan size and rampage throughout the city and the boys must find a way to save their simian friend before the army takes him down.

An ivory ape escapes from a freighter and makes its way to Bermuda. Two anthropologists want to save it, but the local authorities hire a big-game hunter to track it down and kill it.