Besætningen på rumskibet Covenant er på vej til en afsidesliggende planet på den anden side af galaksen, da de opdager, hvad de tror er et uopdaget paradis. Planeten viser sig dog hurtigt at være et mørkt og farefuldt sted, og alt andet end paradis de havde forestillet sig. Da de opdager en trussel, der overgår deres mørkets fantasier, bliver de tvunget til et desperat flugtforsøg fra planeten.

Et hold forskere rejser gennem universet i rumskibet Prometheus på en tur, der har til formål at udforske fremmede livsformer i rummet. Da de finder en mørk og mystisk hule (og om muligt en ny livsform), er lykken gjort, men den viser sig at være kort. Forskerholdet ender nu som strandet på en fremmed planet i det mørkeste hjørne af universet, og imens de må kæmpe for deres overlevelse, går det op for dem, at rædslerne ikke blot er en trussel mod dem selv, men en trussel mod hele menneskeheden.

Den amerikanske specialagent Leon S. Kennedy sniger sig ind i et lille østeuropæisk land for at efterforske rygter om, at der bruges bioorganiske krigsvåben. Straks efter ankomsten, beordrer den amerikanske regering ham til øjeblikkeligt at forlade landet. Leon er fast besluttet på at afsløre sandheden, så han vælger ikke at adlyde ordren og begiver sig ud på slagmarken for at stoppe den kæde af tragedier, som forårsages af de bioorganiske våben.

Den tidligere special forces Oberst, Dale Murphy, har samlet seks fysisk toptrænede og stærkt motiverede deltagere til sit Ultimate Survivor show, der skal optages i en afsides del af West Virginia: Mara, der er producerens veninde og sidste øjebliks deltager, skateboarderen og skørtejægeren Jonesy, Elena, der vil gøre hvad som helst for at blive en stjerne, Nina, der har haft et mildest talt problematisk liv, Jake, hvis football skade fik ham smidt ud af universitetet og den benhårde Armybabe, Amber, der ikke er til drenge ...

Piloten, Rick Janssen (Sam Worthington), er udvalgt til et militært eksperiment for at skabe et menneske, som kan overleve det hårde klima på Saturns måne, Titan. Eksperimentet er en succes og giver Rick superkræfter, men skaber også livsfarlige bivirkninger der truer Rick og hans familie,og måske endda hele menneskeheden.

Et zombie-angreb forårsager kaos i Harvardville Airport. Leon S. Kennedy og Claire Redfield, der bekæmpede den frygtindgydende Umbrella Corporation under tragedien i Raccoon City 7 år tidligere, er tilbage. I hæsblæsende, ægte Resident Evil-stil er de klar til at kæmpe mod en hævntørstig kriger, hvis familie blev dræbt i Raccoon City. Den dødelige G-virus slippes løs, og et nyt muteret monster kommer på krigsstien. Vil det lykkes Claire og Leon at destruere virussen, før historien gentager sig selv?

En flok teknologiafhængige teenagere er på rehabiliteringslejr i skoven, hvor en uhyggelig kraft forsøger at sende dem offline for evigt.

A boy takes in a stray dog, later finding out that its an ultra-intelligent runaway from a genetic research lab. Unbeknownst to him, the dog is being stalked by another escaped creature thats not quite so friendly.

When something horrible happens to the only survivor of a bloody massacre, an insecure rookie cop must overcome his fears to stop further carnage.

An alien microbe lands in remote Siberia in the 1950's. In the year 2004, US scientist working at a top secret underground lab in Alaska clone the microbe. A garbled distress signal is heard from the lab just before a complete lock down of the facility. This is the last word sent out from the scientists. A team of scientists and military personnel are in charge of finding out what went wrong.

A genetically mutated ape escapes from a top secret facility and wreaks havoc in Hollywood.

An American scientist up to no good (as usual) by creating the half-pterodactyl, half-barracuda: Pteracuda. When the creature inevitably escapes, it's up to Sharktopus to stop him.

After a young man is bitten on the hand by a radioactive snake, his hand changes into a lethal snake head, which attacks everyone he comes into contact with. Also, his body becomes filled with snakes. Now, he must prevent himself from hurting others.

A Retrovirus, which was conceived as a tool for industrial genetic engineering, has gotten out of control and is spreading rapidly. While it crosses all organisms within our ecological system completely indiscriminately (mixing plant with animal and humans) most plants prove more resistant because of their complex DNA. However, the simple genes of the plants lead humans to become grotesque mutations, in most cases even to death. Within one week, 90% of mankind are either extinct or no longer human. However, a small fraction of the earth?s population remains immune to the virus and must survive in this new and constantly changing ecological system. Tom cellar is one the survivors and on an old military base in the Eifel he has entrenched himself. Further survivors come together and succeed in carving out a life in this new world. But the GMOs - the ?genetically modified organisms? - constantly develop themselves further, and soon the fence of the base offers no more protection.

In the near future after state-owned farms produce genetically modified crops, a giant mutated insectoid creature is discovered living in the wetlands of Japan. After several civilians are killed, the military steps in to end the creature's reign of terror. This is a student film project from Musashino Art University.

When Dr. Walter Hall creates a drug that turns men into rampaging creatures, the government forces him to continue his unorthodox experiments. Coerced by the authorities, he injects the serum into an unsuspecting derelict and unleashes an unspeakable terror upon the community-a monster-part man - part reptile...part alien. Now twenty years later, the creature has resurfaced and Dr. Hall must literally put the devil to rest by reopening the old experiment by once again confronting the evil he knows as...VILE 21.