120 Minutes is a television show in the United States dedicated to alternative music, originally airing on MTV from 1986 to 2000, and then on MTV's sister channel MTV2 from 2001 to 2003.

After its cancellation, MTV2 premiered a replacement show called Subterranean. A similar but separate VH1 Classic program, VH1 Classic 120 Minutes, plays many classic alternative videos that were regularly seen on 120 Minutes in its heyday.

120 Minutes returned as a monthly series on MTV2 on July 30, 2011, with Matt Pinfield as host.

120 Minutes is a show on MTV Two that was broadcast nightly at 1am. In the tradition of the US show of the same name, it showcased music videos from "the newest, most innovative acts in rock, left field and electronic music".

In the United Kingdom and the rest of Europe, 120 Minutes was originally featured on MTV Europe from 1990, hosted during its first years by VJ Paul King and, from 1994 on, by ex-Wonder Stuff frontman Miles Hunt. It disappeared in late June 1995, but was replaced by a similar show, Alternative Nation, which was shown on MTV Europe on Tuesday nights at midnight CET until July 2010. 120 Minutes returned in 2003 to MTV2 Europe, replacing a similar show, 2eclectic, which had sporadically occupied various late-night slots.