The Grand Budapest Hotel tells of a legendary concierge at a famous European hotel between the wars and his friendship with a young employee who becomes his trusted protégé. The story involves the theft and recovery of a priceless Renaissance painting, the battle for an enormous family fortune and the slow and then sudden upheavals that transformed Europe during the first half of the 20th century.

A rogue scientist near a small desert town arouses the suspicion of the town's doctor when his lab assistant is found dead from a case of acromegaly, which took only four days to develop. As the doctor investigates, aided by the scientist's new female assistant, they discover that something is devouring local cattle and humans in increasingly large quantities.

A tramp gets drunk in a hotel lobby and, upstairs, causes some misunderstandings between Mabel, two hotel guests across the hall from her room, and Mabel's visiting sweetheart.

To avoid the rigors of the law, Gilda flees New Orleans and hides on a Caribbean island where the worst criminals can ask for asylum. Besieged by the scum of the earth, Gilda will soon find out that she has found refuge in hell.

A score of amateur children sing and dance in costume in a multi-act musical revue.

In a smudgy hotel, guests and staff have a run in with fate.

Tofiq and his father watch Snake in the Eagle's Shadow, and because of their differences they get into a debate; to settle it, they decide to have a showdown. Tofiq loses and, because of it, is forced to leave their house and go into the city. There he encounters someone else and they start having beef, and this goes on until the end of the movie.