Set in a small restaurant in the corner of a shopping district. The unusual eatery is only open after midnight, and its standard menu consists of just a single choice. However, the customers still come for the amusing chatter and the proprietor's willingness to cook any dish that they request. This drama depicts the lives of the restaurant's patrons, including a yakuza, an unsuccessful actor, a group of office ladies, a newspaper delivery boy, and a stripper.

Het verhaal, dat zich afspeelt in de fictieve stad Kamurocho, volgt twee lijdlijnen - 1995 en 2005. In 1995 proberen vier vrienden te ontsnappen aan hun strenge leven in een weeshuis en duiken in de door de Yakuza geleide onderwereld van Kamurocho in 1995. Ondertussen, in 2005, is hun vriendschap uit elkaar gevallen, terwijl de spanningen tussen de Tojo-clan en de Omi-clan een kookpunt bereiken.

To deal with the increasing violent crime rate in the Shinjuku area of Tokyo, a special investigation team is formed at the Shinjuku Police Station. Detective Shunsuke Yamashita and Detective Keiichi Tashiro begin work at the special investigation team. Detective Shunsuke Yamashita doesn't care about details and says what he thinks. Meanwhile, Detective Keiichi Tashiro is diligent and enthusiastic with his investigative work. The two men frequently argue, but also cooperate to solve the cases.