Billy Hill and Jack 'Spot' Comer were among the most notorious criminals in London up until the 1950s. Dramatising the violent reign of two of London's most notorious gangsters, Billy Hill (Leo Gregory) and Jack 'Spot' Comer (Terry Stone), ONCE UPON A TIME IN LONDON charts the legendary rise and fall of a nationwide criminal empire that lasted until the mid-fifties and which paved the way for the notorious Kray Twins and The Richardsons. This is the story of their rise and fall.

The story of a group of intoxicated lads driving to a music festival, who seriously injure a young nurse in a night time collision. They make matters far worse by trying to cover up their mistake by hastening the demise of their victim. This, they come to seriously regret as they realise the extent of their culpability and as an unseen killer proceeds to take brutal vengeance.