In the middle of a routine patrol, officer Daniel Carter happens upon a blood-soaked figure limping down a deserted stretch of road. He rushes the young man to a nearby rural hospital staffed by a skeleton crew, only to discover that patients and personnel are transforming into something inhuman. As the horror intensifies, Carter leads the other survivors on a hellish voyage into the subterranean depths of the hospital in a desperate bid to end the nightmare before it's too late.

While working undercover as a bodyguard to arms dealer Harry, former-soldier-turned-secret-service-agent Ewan survives a bloody shootout with a member of an Islamic terrorist cell who steals Harry's briefcase full of Semtex explosives and escapes. Ewan's spymasters task Ewan with hunting down the cell members and retrieving the briefcase.

The sordid lives of an addict, an ex-con, and a luchador collide when an organ harvesting caper goes very, very wrong.