January 1978. After their success in England, the punk rock band Sex Pistols venture out on their tour of the southern United States. Temperamental bassist Sid Vicious is forced by his band mates to travel without his troubled girlfriend, Nancy Spungen, who will meet him in New York. When the band breaks up and Sid begins his solo career in a hostile city, the turbulent couple definitely falls into the depths of drug addiction.

Infatuated with the idea of becoming rich, college student Jonathan Corliss secretly dates Dorothy Carlsson to gain the approval of her wealthy father. When Dorothy tells Jonathan that she is pregnant and that her father will deny her inheritance if he finds out, Jonathan murders her, but he stages her death as a suicide. As Jonathan works his way onto Mr. Carlsson's payroll, Dorothy's twin sister, Ellen, investigates the apparent suicide.

A gang of bank robbers with a suitcase full of money go to the desert to hide out. After burying the loot, they find their way to a surreal town full of cowboys who drink an awful lot of coffee.