Since he won the lottery, Pancho, a Jack Russell Terrier dog, lives a life full of luxury. His personal assistant manages his fortune. After trying to strike a deal with Pancho to make him become a star of the toy industry, Investor Montalbán will try to kidnap Pancho by any means. Pancho will discover real life dangers, and understand real wealth is in friendship.

The story of the Balmis Expedition, funded by the King of Spain, to bring the smallpox vaccine to Spanish America.