Jerry Shaw and Rachel Holloman are two strangers whose lives are suddenly thrown into turmoil by a mysterious woman they have never met. Threatening their lives and family, the unseen caller uses everyday technology to control their actions and push them into increasing danger. As events escalate, Jerry and Rachel become the country's most-wanted fugitives and must figure out what is happening to them.

Drew Baylor is fired after causing his shoe company to lose hundreds of millions of dollars. To make matters worse, he's also dumped by his girlfriend. On the verge of ending it all, Drew gets a new lease on life when he returns to his family's small Kentucky hometown after his father dies. Along the way, he meets a flight attendant with whom he falls in love.