L'ex agente della CIA Shepherd, in carcere per aver tradito il suo Paese, viene reclutata dallFBI per contribuire alla cattura del terrorista Tal con cui ha collaborato.

Gli uomini di Tal uccidono un ex agente della CIA Dean Merriman - sottraendogli il portatile e la password dellagenzia di sicurezza privata per la quale lavora.

Una pattuglia della DEA viene uccisa a largo delle coste della Colombia per mano del cartello Morales.

Lagente Keaton e la sua squadra, su suggerimento di Shepherd, si mettono sulle tracce di Aksoy, un militante turco affiliato agli anti-americani del Fronte Rivoluzionario.

Shepherd convince Keaton che Cruz e' la talpa di Tal; la squadra inizia a sorvegliarla nella speranza che la giovane possa condurli dal terrorista.

After a bomb explodes in Jersey City, the Cointel team captures a key planner, Sam Fathi, who can lead them to Tal, the mastermind behind the bombing. When Sam proves difficult to break, Shepherd convinces Keaton to detain a former Egyptian intelligence officer to help, leading to an urgent mission to stop another bomb from going off.

When the FBI intercepts stolen NSA software intended for Tal, Keaton uses the technology as an opportunity to go on the offensive and sends Shepherd undercover. Keaton must choose between catching Tal or saving the life of an innocent teenager.

Flashbacks to the past reveal the fateful events that led CIA Deputy Director Erica Shepherd to betray her country and the ensuing investigation that put her on a collision course with Will Keaton.

After a major Tal operative escapes CIA custody, Shepherd returns to Langley to help track the fugitive down. Shepherd and Keaton discover the CIA is withholding vital information on Tal, so they spy on the CIA to find out what the agency knows.

When a group of contractors working for the CIA is murdered, Keaton and the team discover the CIA is keeping secrets from the FBI regarding Tal. Shepherd's ex-husband finds out that Hannah has been lying and visiting Shepherd.

When a highly sophisticated Tal operative evades FBI custody and flees to the Swiss embassy, the Cointel team must go under cover. What begins as a smooth counterintelligence operation quickly devolves into a tense hostage situation.

Keaton and his team are able to intervene and stop the assassination of a high-profile congresswoman; Shepherd interrogates the congresswoman, who had previously used Shepherd's treason conviction as a launching pad for her political career.

Tal's war on the CIA expands to two fronts; Keaton and the CoIntel team must locate the domestic target before Chigorin launches an all-out assault on the unsuspecting innocents; Shepherd convinces Keaton to let her go to Cuba to thwart Tal's attack.