Three people enter an abandoned silver mine and are attacked by a strange creature, which drains the water from their bodies. Rosalita thinks it's a ghost, but Burt knows it must be something else, especially when two government agents arrive in Perfection.

A team of scientists find a deadly strange animal/plant hybrid growing in the valley. Burt, Tyler and Cletus work with them to figure out how to stop it before it spreads even further. Meanwhile, Perfection has to deal with an over-excited tourist named Larry.

Larry returns to Perfection and wants to learn more about Cletus Poffenberger. Tyler tells him the story of when the Perfection residents first met Cletus and had to face his increasingly dangerous pet, Four-Twelve.