Peter is saved from the lobotomy when Michael and Amanda break into the hospital, but ""Betsy"" captures them and locks them in the boiler room. Nurse Benson realizes that Kimberly is crazy, and tries to release the trio. ""Betsy"" stops them from escaping, but Michael is able to talk Kimberly back to reality. An orderly suspects that Michael has brainwashed Kimberly, and tries to attack him. Kimberly rescues Michael, but falls off a twenty-foot platform in the scuffle. Syd tries to dissuade Jane from continuing her murder plot. Jane offers Samantha a job and apartment in exchange for information on other offers on the store. Jane embezzles money from Richard to buy the space. Matt begins to recover from his illness. Jo is stunned when Dominick proposes. Jake tries to push Alison away when she expresses a romantic interest in him.

Peter is arrested for Bobby's murder. His alibi, Kimberly, drifts into a coma. Amanda marries Peter in a jailhouse ceremony so that she won't have to testify against him. A detective reveals to Amanda that Peter is lying about his identity. Dominick prepares to leave for a yearlong relief mission in Bosnia. He asks Jo to come with him, but she is torn. Matt struggles to catch up with his studies after he is released from the hospital. A classmate gives him amphetamines to help him stay awake, and he becomes addicted. Jake pushes Alison to give Billy another chance. She sleeps with Jake, while Billy is left alone in the rooftop restaurant he had rented for their date. Jane attempts to shoot Richard in his garage, but Syd has removed the bullets. Richard tries to rape Jane, but Sydney conks him in the head with a shovel. After discovering that Richard does not have a pulse, the sisters drive off and bury the body along a hill. As they drive away, Richard's hand shoots up from the dirt.

Jane and Sydney escape when Jane hits Richard in the gut with a shovel. As a deputy is driving Jane and Syd to meet Samantha, they see Richard come out of a grocery store. Richard is killed in a shootout. At the morgue, Jane stabs his body with a brooch to make sure that he is dead. A sheriff returns their money, and orders them out of his town. Jane stops a bewildered Sam from moving out. Sydney invests her money in Jane's boutique. Amanda threatens Kimberly when she refuses to perjure herself. Kimberly later ensures Peter's release when she recalls a waiter who can serve as his alibi. Amanda is angry when Taylor shows up at the courthouse. Billy mistakenly believes Alison has invited him to her apartment, and gets into a fist fight with Jake when he finds him there. One of Matt's professors suspects that he is on drugs.

Peter fires Sydney after learning that she sold his house (which he had listed as a company asset) to pay the practice's debts. Peter has to move into Amanda's apartment. Sydney goes to work at the boutique. Billy goes on a date with Sam, but is still preoccupied with Alison. At the grand opening of the boutique, a drunken Billy announces that Alison and Jake are sleeping together. An outraged Jane throws Jake and Alison out of the store. After confronting Alison at her new apartment, Jane accidentally trips over some oily rags and sets the building on fire. Kimberly is ordered to appear before the medical board. She voluntarily surrenders her license and takes a job as the Burns/Mancini receptionist. Taylor has an appointment with Peter, and asks Amanda to handle advertising for the restaurant. Michael warns Matt to get clean. Matt nearly suffers a heart attack while high on PCP. He is later arrested for soliciting an undercover cop.