Lily, Carmen, Mary Cherry and Brooke are peacefully riding Lily's car when they pass by a car crash and notice the Gremlin's license plate, TUNA69, and realize that the car belongs to their classmate April Tuna. The entire school is touched by her death and they make a memorial service in her honor. Everyone's feeling guilty about how they treated her. Josh gets a new hairstyle and joins the ""mullets"" club. Nicole finds out that the cafeteria lady is in fact her long lost birth mom. Sam gets an email from Harrison telling her he loves her and asks her to choose between him and George. Nicole gets an email too, saying what a bitch she is. She admits being a bitch at the memorial service, and April suddenly appears, saying she was not in the car that got crashed.

Ms. Glass wants all the students to write down where did they go for Spring Break and how many they slept with, so, in her own words, she can judge them. Most of the gang say they went to Cancun, and Harrison writes that he went to Yemen as his nose starts to bleed. Ms. Glass deduces he has been infected with the Rift Valley fever that is contaminating everyone in Yemen. Just as Sam was trying to talk to him by his locker, they are both isolated from the rest of the people and the school is shut down in quarantine. During Chemistry, Mary Cherry receives a call in her cell phone from someone who knows what she really did for Spring Break - a low-budget soft porn scary movie - and she has to run for her life as she is chased to be killed. Meanwhile, Lily tells April what they really did for SB. They intended to go to Cancun, but they all stayed in LA and had SB in different ways. Nicole is elected to attract the killer, but since she's not a virgin, and only virgins get chased by killers