When the grim reaper comes to collect the soul of megamogul Bill Parrish, he arrives with a proposition: Host him for a "vacation" among the living in trade for a few more days of existence. Parrish agrees, and using the pseudonym Joe Black, Death begins taking part in Parrish's daily agenda and falls in love with the man's daughter. Yet when Black's holiday is over, so is Parrish's life.

When disillusioned Swedish knight Antonius Block returns home from the Crusades to find his country in the grips of the Black Death, he challenges Death to a chess match for his life. Tormented by the belief that God does not exist, Block sets off on a journey, meeting up with traveling players Jof and his wife, Mia, and becoming determined to evade Death long enough to commit one redemptive act while he still lives.

Death takes a human form and visits Earth to try to find out why humans want so desperately to cling to life. He unexpectedly falls in love with a beautiful young woman.

Keith is a Japanese twenty-something who is followed by Death in various disguises. When he finally faces her, Death tells him that he has only 12 hours to live and he needs to make the most of it